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Compounding pharmacies operate under distinct legal pathways: Section 503A applies to state-licensed pharmacies compounding medications for individual patients Section 503B applies to FDA-registered outsourcing facilities that compound medications in bulk FDA Safety Alerts on Compounded Semaglutide The FDA has issued warnings regarding dosing errors associated with compounded semaglutide, particularly when supplied in multi-dose vials

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Rapid weight loss and biomechanical changes: Patients achieving significant weight reduction may experience temporary musculoskeletal adjustment

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